Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Reducing Toxicity of Immune Therapy Using Aptamer-Targeted Drug Delivery.

Modulating the function of immune receptors with antibodies is ushering in a new era in cancer immunotherapy. With the notable exception of PD-1 blockade used as monotherapy, immune modulation can be associated with significant toxicities that are expected to escalate with the development of increasingly potent immune therapies. A general way to reduce toxicity is to target immune potentiating ...

advances in targeted drug delivery

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Targeted drug-delivery approaches by nanoparticulate carriers in the therapy of inflammatory diseases.

Limitations in therapy induced by adverse effects due to unselective drug availability and therefore the use of potentially too high doses are a common problem. One prominent example for this dilemma are inflammatory diseases. Colloidal carriers allow one to improve delivery of drugs to the site of action and appear promising to overcome this general therapeutic drawback. Specific uptake of nan...